AN OVERVIEW: FORMULATION AND EVALUATION FOR FAST DISSOLVING TABLETS
نویسندگان
چکیده
منابع مشابه
Fast Dissolving Tablets: Preparation, Characterization and Evaluation: an Overview
Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researcher developed the fast dissolving tablet (FDT) with improved patient compliance and convenience. FDTs are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. FDTs overcome the disadvantages of con...
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Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, mouth dissolving drug delivery systems (MDDDS) have acquired an important position in the market by overcoming previously encountered administration problems and contributing to extension of patent life. MDDDS have the unique property of rapidly disin...
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Fast dissolving tablets of clonazepam were prepared by direct compression method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of crospovidone and microcrystalline cellulose. Crospovidone (2-8% w/w) was used as superdisintegrant and microcrystalline cellulose (20-40% w/w) was used as di...
متن کاملFormulation of Fast-Dissolving Tablets of Promethazine Theoclate
Purpose: To optimize and formulate promethazine theoclate fast-dissolving tablets that offer a suitable approach to the treatment of nausea and vomiting. Method: The solubility of promethazine theoclate was increased by formulating it as a fast-dissolving tablet containing β-cyclodextrin, crospovidone, and camphor, using direct compression method. A 3 3 full factorial design was used to investi...
متن کاملFormulation and Evaluation of Mouth Dissolving Tablets of Cinnarizine
The purpose of this research was to develop mouth dissolve tablets of cinnarizine by effervescent, superdisintegrant addition and sublimation methods. All the three formulations were evaluated for disintegration time, hardness and friability, among these superdisintegrant addition method showed lowest disintegration time; hence it was selected for further studies. Further nine batches (B1-B9) w...
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ژورنال
عنوان ژورنال: Journal of Harmonized Research in Pharmacy
سال: 2019
ISSN: 2321-0958
DOI: 10.30876/johr.8.4.2019.55-64